Latest Research News – March and April 2017 – Ataxia

Latest Research News – March and April 2017

Latest Research News – March and April 2017

An encouraging report on a study using RNA-targeted therapies in both ALS and SCA2 

Scientists report a significant step toward combatting two degenerative brain diseases. A targeted therapy developed by scientists at University of Utah Health slows the progression of Spinocerebellar Ataxia type 2 (SCA2) in a mouse model of this condition. In a parallel collaborative study, led by researchers at Stanford University, a nearly identical treatment improves the health of mice that model Amyotrophic Lateral Sclerosis (ALS). You can read the press release here

Posted: 18/04/2017

Scientists use gene editing technique to restore production of frataxin protein in mice

Researchers have reported in a recent publication encouraging results about a study where they have successfully corrected a mutated frataxin gene in a mouse model of FA, a model which Dr Mark Pook created with Ataxia UK’s funding. You can find more information and the publication here.

Posted: 05/04/2017

A recent publication is reporting a potential new therapeutic target for Friedreich’s ataxia 

RNF126 depletion results in frataxin accumulation in cells derived from FRDA patients, highlighting the relevance of RNF126 as a new therapeutic target for Friedreich’s ataxia. A combined therapy aimed to increasing frataxin levels, either by promoting its gene transcription or through gene therapy or protein replacement, and simultaneously interfering with its RNF126-mediated degradation could be envisioned. You can read the full article here

Posted: 03/03/2017

SUBSCRIBE TO OUR NEWSLETTER

Something went wrong. Please check your entries and try again.
fundraise image

FUNDRAISE FOR US

Take part in a challenge or create your fundraiser. Every penny you raise will help those affected by ataxia.

Donate Image

DONATE

To make either a one off or recurring donation which will help fund research into treatments and cures and supports those affected ataxia

Volunteer Image

VOLUNTEER WITH US

Support the ataxia community and volunteer with Ataxia UK. From social media to telephone befriending, there are loads of ways you can make a difference to someone's life.

Donate Now
Welcome to our new site! We hope you like it.
As it's brand new, there may be a few temporary glitches such as broken links - we are working on getting these all fixed ASAP. If you'd like to give us any feedback or let us know if something isn't quite right, please email website@ataxia.org.uk
+
Scroll to Top