Ataxia UK funds a wide variety of research projects. Below is a list of all projects currently being funded, and of projects that have ended in the last 2 years.

Friedreich’s Ataxia 

Project

Principal Researchers & Institution

Funders & Awards

RNA-FISH evaluation of the FXN gene transcription: focus on cell-to-cell and cell
cycle modulation, and the role in origin and evolution of the
Friedreich's ataxia GAA-repeat mutation

Prof Antonella Russo, University of Padova (Italy)

Research project small grant 

Award: £4,800

Funders: Ataxia UK

Effect of vitamin D in frataxin-deficient DRG neurons from rat and iPS cells obtained from FA patients

Dr Joaquim Ros, Dr Jordi Tamarit & Dr Marta Llovera, Universitat de Lleida (Spain)

Research project grant 

Award: £42,000

Funders: Ataxia UK, ACAH, Ataxia Ireland

Studying G-CSF as a potential treatment for Friedreich’s Ataxia

Dr Alastair Wilkins, Dr Kevin Kemp, & Professor Neil Scolding, 
University of Bristol (Bristol, UK)

Research project grant

Award: £58,061

Funders: Ataxia UK, FARA

European Friedreich's Ataxia Consortium for Translational Studies (EFACTS)

Jörg B. Schulz, University Hospital RWTH Aachen, (Germany), Paola
Giunti University College London (London, UK), Alexandra Dürr,
UPMC Université Paris (France), Mathieu Anheim, Hôpitaux Universitaires de Strasbourg
(France), Sylvia Boesch, Medical University Innsbruck (Austria), Caterina Mariotti, Fondazione
IRCCS Istituto Neurologico “C.Besta” (Italy), Enrico Bertini, Bambino Gesù Children’s
Research Hospital (Italy), Francesc Palau, Pediatric Institute for Rare Diseases – IPER (Spain)

Research project grant

Award: 97,000 euros

Funders: Ataxia UK, AFAF, Ataxia
Ireland, FEDAES, DHAG, AISA

Effectiveness of LSVT in improving communication in people with Friedreich’s ataxia

Prof Anja Lowit, Strathclyde University (Glasgow, UK)

Research project small grant

Award: £8,997

Funders: Ataxia UK, Swiss Association of Friedreich’s Ataxia (ACHAF)Finding a treatment for Friedreich’s ataxia: identification and characterisation of frataxin up-regulating compounds from the Pfizer’s small molecule library’

Finding a treatment for Friedreich’s ataxia: identification and characterisation of frataxin up-regulating compounds from the Pfizer’s small molecule library’

Pfizer (US & UK), Dr Paola Giunti, University College London & Prof Richard Festenstein, Imperial College London (London, UK) & Dr Michele Lufino, Oxford University (Oxford, UK)

Consortium grant

Funders: The consortium has been funded by Pfizer with some financial support from Ataxia UK.

Exploring Ca2+ signalling in a Friedreich’s ataxia mouse model

Dr Paola Giunti, Dr Sandip Patel & Mr Alexander Brown, University College London (London)

PhD studentship grant

Award: £82,000

Funders: Ataxia UK, UCL grand challenge studentship

Beta-band EMG-EMG coherence: a novel, painless and simple screening test for the onset of corticospinal tract disease/dorsal root ganglionopathy in Friedreich’s ataxia

Dr Mark Baker, Prof Stuart Baker, & Prof Patrick Chinnery, Newcastle University (Newcastle, UK)

Research project grant (joint call for research in biomarkers) 

Award: £84,446

Funders: Ataxia UK, GoFAR, FARA

An investigation to determine the efficacy and safety of lentivirus mediated FXN gene delivery for the correction of Friedreichs ataxia 

Dr Michael Themis & Dr Mark Pook, Brunel University London (London, UK)

Research project grant

Award: £82,355

Funders: Ataxia UK, Friedreichs Ataxia Research Alliance (FARA) US, Friedreichs Ataxia Research Alliance (FARA) Australia

Cerebellar Ataxia

Project

Principal Researchers & Institution

Funders & Awards

Discrimination of wild type and mutant ATXN3 mRNA levels by qPCR: protocol design and implementation

Dr Mafalda Raposo, Dr Manuela Lima, University of the Azores
(Portugal)

Research project small grant

Award: £5,000

Funders: Ataxia UK

Modelling the molecular pathogenesis of ARSACS with patient cells: disrupted
proteostasis in ARSACS neurons

Professor Paul Chapple,
Queen Mary University of London & Professor Michael Cheetham, University College London (London, UK)

Research project grant 

Award: £70,000

Funders: Ataxia UK, The ARSACS Foundation

Neuroprotective therapeutic approach for Spinocerebellar Ataxia type 2:
pharmacological targeting of AMPK 

Dr Clévio David Rodrigues Nóbrega, Universidade do Algarve (Portugal)

Research project grant 

Award: £9,500

Funders: Ataxia UK

Novel pharmacological approach to treat Episodic ataxia type 1

Dr Paola Imbrici, University of Bari (Italy)

Research project small grant 

Award: £5,000

Funders: Ataxia UK

Detecting retinal changes in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) and other ataxias using optical coherence tomography (OCT)

Dr Paola Giunti, University College London (London, UK)

Research project small grant

Award: £4,500

Funders: Ataxia UK


For information on Ataxia UK funded research that has ended in the last few years, click here.